Integumentary System

Shyam Sunder , 19-Nov-2025

Integumentary System — IIHCM

Integumentary System

The integumentary system includes the skin, hair, nails, sebaceous glands and sweat glands.

Specialty Dermatology   •   Physician Dermatologist

Structure of Skin

The skin is divided into two primary layers:

Epidermis
The outer layer of skin.
Dermis
The inner layer of skin.

Functions

  • Protecting internal organs against infection, injuries and harmful chemicals.
  • Maintaining body temperature.
  • Synthesizing vitamin D when exposed to sunlight.

Skin lesions

Human skin structure diagram
Figure: Primary and Secondary Skin Lesions
  • Vesicles – Small blisters with clear fluid < 10 mm.
  • Bulla – Large blisters with clear fluid > 10 mm.
  • Cyst – A sac-like structure filled with fluid or semisolid material.
  • Fissure – A crack-like opening or slit.
  • Erythema – Redness of the skin.
  • Nodule – Large elevation in the skin; movable lumps.
  • Papule – Small elevation in the skin; movable lumps.
  • Polyp – Mushroom-like growth on a slender stalk which protrudes outwards.
  • Macule – A flat discoloration of skin.
  • Wheals – A swollen, discoloured area of skin.
  • Pustule – Elevation containing pus.
  • Ulcer – Lesion in the mucous membrane that may lead to bleeding/inflammation.

Symptoms

  • Any skin lesions
  • Disturbances of skin sensation
    • Anesthesia
    • Hypoesthesia
    • Paresthesia
    • Hyperesthesia
  • Rashes, possibly with itchiness or pain
  • Swellings, lumps or masses
  • Discolored skin patches (abnormal pigmentation)
  • Dry skin
  • Open sores, lesions or ulcers
  • Peeling skin
  • Red, white or pus-filled bumps
  • Scaly or rough skin

Conditions & Diseases

  • Dermatitis / Eczema – Inflammation of skin due to allergy to certain foods, drugs or chemicals.
  • Cellulitis – Inflammation of skin due to infection.
  • Urticaria (Raised wheals) – Severe itching caused by contact with irritants or allergens.
  • Alopecia – Loss of hair.
  • Petechia – Small pinpoint haemorrhages.
  • Wart – Thickening of epidermis due to viral infection.
  • Varicella – Viral infection (chickenpox).
  • Cyanosis – Bluish/purple discoloration of skin due to lack of oxygen.
  • Abrasion – Removal of superficial layer of skin.
  • Vitiligo – Irregular milky-white patches surrounded by normally pigmented skin.
  • Xeroderma – Excessive dryness of skin.
  • Tinea – Group of fungal infections (ringworm).
  • Tinea pedis – Athlete's foot: itching, scaling, redness of toes.
  • Tinea barbae – Fungal infection of beard area (face & neck).
  • Onychomycosis – Fungal infection of nails.
  • Albinism – Inability to produce melanin.
  • Hematoma – Collection of blood under the skin.
  • Pruritus – Itching.
  • Lipoma – Benign fatty tumour.
  • Herpes simplex – Viral infection due to herpes simplex virus.
  • Hyperhidrosis – Excessive sweating.
  • Impetigo – Bacterial skin infection causing red sores that break and ooze.
  • Psoriasis – Chronic autoimmune disease affecting scalp, face, elbows, genital area, knees, buttocks.

Investigations

  • Biopsy
  • Laboratory tests

Skin Procedures

  • Biopsy – Removal of a piece of skin to be sent to the laboratory.
  • Excision – Surgical removal of abnormal growths.
  • Repair – Suturing of wounds.

Author: Dr. Shyam Sunder • IIHCM